Tips for Choosing the Right Vial for Chromatography

05/22/2022


When performing chromatography, choosing the right chromatography vial can make a huge difference in the quality of your results. Better-quality vials will help protect your samples from contamination and allow you to perform the analysis without worrying about leaking. When selecting chromatography vials, make sure to check the manufacturer's recommendations, as these can affect the viability of your samples. By following these tips on this blog, you can choose the right vial for your chromatography applications and maximize the ROI of your processes.

Choosing the right chromatography vial depends on the size of the sample you will be analyzing. Standard sizes include 8x40mm, 15x45mm, and 12x32mm. Vials for gas chromatography use 8x40mm vials, while those used in liquid chromatography require 12x32mm vials. Other sizes are available, including the 9mm mini volume vial.

The type of vials used in chromatography is also important. For general purpose applications, chromatography-approved vials are appropriate. For specialized applications, such as high-selectivity research, you may need to use higher-sensitivity vials. In addition, analytical vials need to be cleaned before use and be free from silanol groups. To ensure the reproducibility of your results, the right vials should undergo additional processing before being shipped to your laboratory.

The size of a chromatography vial depends on the volatile and stable nature of the compounds you're testing. You can choose the size of a vial based on your needs by considering the size and type of your autosampler. Most chromatography vials have an outer diameter of five or six millimeters, which allows you to use a wide range of inserts to sample different samples.

Glass vials are ideal for use in chromatography because they are pure and free from contamination. Glass is also a good choice for chromatography because it is resistant to heat. This means that it's suitable for samples that are sensitive to UV light or are difficult to examine visually. Plastic vials are cheaper than glass ones, but not all of them are the same. The best plastic vials are made of polypropylene or polymethyl pentene.

Another important consideration when choosing chromatography vials is the closure. The caps are usually made of aluminum or plastic and are designed to crimp on the top of the vial. Other types of caps are pre-slit to make needle penetration easier and safer. In addition, there are various types of cap liners available, including electronic models. Make sure you choose a vial closure that is compatible with the solvent you're testing.

Glass chromatography vial is also ideal for chromatography because they are non-adsorbing or minimally adsorbing. They are also good for achieving high reproducibility between batches or replicates. Moreover, glass vials can be pre-processed to ensure the consistency of the analytes' concentrations. Glass vials can also help you avoid the errors caused by adsorption, which can delay the development of a therapeutic. For more understanding of this article, visit this link: https://en.wikipedia.org/wiki/Chromatography.

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